Personally I think it is. Over the years I've seen enough Donkey Kong players who play this game excessively who are prone to anger or mental health issues seem to have their mental difficulties amplified.
But perhaps this is a common theme with doing anything excessively, and I'm just seeing examples of Donkey Kong because it's something I have an interest in.
You could say the same thing about chess as a few great chess players seem to have lost their minds over the years
Just my two cents